{
  "id": 674081,
  "title": "What models should we use",
  "url": "/competitions/stanford-rna-3d-folding-2/discussion/674081",
  "author_name": "Leo Withrow",
  "post_date": "2026-02-18T15:26:51.547000",
  "votes": 1,
  "comment_count": 3,
  "views": 0,
  "content": "<p>I’m new to the competition, does anyone know if it’s a good idea to use alpha genome as a model? If not, which model should I use?</p>",
  "messages": [
    {
      "id": 3407829,
      "postDate": "2026-02-19T08:41:36.470Z",
      "content": "<p>it seams Alpha Genome can only be accessed using API (<a href=\"https://github.com/google-deepmind/alphagenome)\" target=\"_blank\">https://github.com/google-deepmind/alphagenome)</a>. But in our nootbook, the internet accessing is disabled.  And AlphaGenome focuses on DNA sequences (long genomic contexts, gene expression, chromatin, splicing across species), not directly on RNA secondary/tertiary folding or 3D coordinate prediction.</p>",
      "rawMarkdown": "it seams Alpha Genome can only be accessed using API (https://github.com/google-deepmind/alphagenome). But in our nootbook, the internet accessing is disabled.  And AlphaGenome focuses on DNA sequences (long genomic contexts, gene expression, chromatin, splicing across species), not directly on RNA secondary/tertiary folding or 3D coordinate prediction.",
      "votes": 1,
      "replies": [
        {
          "id": 3407976,
          "postDate": "2026-02-19T15:08:26.440Z",
          "content": "<p>Do you know which models we should use?</p>",
          "rawMarkdown": "Do you know which models we should use?\n",
          "replies": [
            {
              "id": 3408277,
              "postDate": "2026-02-20T08:17:57.763Z",
              "content": "<p>You can use models like protenix, ribonanzanet, rhofold </p>",
              "rawMarkdown": "You can use models like protenix, ribonanzanet, rhofold ",
              "votes": 1
            }
          ]
        }
      ]
    },
    {
      "id": 3407552,
      "postDate": "2026-02-18T15:26:51.547Z",
      "content": "<p>I’m new to the competition, does anyone know if it’s a good idea to use alpha genome as a model? If not, which model should I use?</p>",
      "rawMarkdown": "I’m new to the competition, does anyone know if it’s a good idea to use alpha genome as a model? If not, which model should I use?",
      "votes": 1
    }
  ],
  "comments": [
    {
      "id": 3407829,
      "author_name": "Qiwei",
      "author_url": "",
      "post_date": "2026-02-19T08:41:36.470000",
      "content": "<p>it seams Alpha Genome can only be accessed using API (<a href=\"https://github.com/google-deepmind/alphagenome)\" target=\"_blank\">https://github.com/google-deepmind/alphagenome)</a>. But in our nootbook, the internet accessing is disabled.  And AlphaGenome focuses on DNA sequences (long genomic contexts, gene expression, chromatin, splicing across species), not directly on RNA secondary/tertiary folding or 3D coordinate prediction.</p>",
      "votes": 1,
      "replies": [
        {
          "id": 3407976,
          "author_name": "Leo Withrow",
          "author_url": "",
          "post_date": "2026-02-19T15:08:26.440000",
          "content": "<p>Do you know which models we should use?</p>",
          "votes": 0,
          "replies": [
            {
              "id": 3408277,
              "author_name": "CHIKONZERO SELEMANi",
              "author_url": "",
              "post_date": "2026-02-20T08:17:57.763000",
              "content": "<p>You can use models like protenix, ribonanzanet, rhofold </p>",
              "votes": 1,
              "replies": []
            }
          ]
        }
      ]
    }
  ],
  "raw_markdown_by_id": {
    "3407829": "it seams Alpha Genome can only be accessed using API (https://github.com/google-deepmind/alphagenome). But in our nootbook, the internet accessing is disabled.  And AlphaGenome focuses on DNA sequences (long genomic contexts, gene expression, chromatin, splicing across species), not directly on RNA secondary/tertiary folding or 3D coordinate prediction.",
    "3407552": "I’m new to the competition, does anyone know if it’s a good idea to use alpha genome as a model? If not, which model should I use?"
  }
}