{
  "id": 145253,
  "title": "Literature Review Thread: Gleason Pattern Classification, Biopsies, Working with Whole Slide Images",
  "url": "/competitions/prostate-cancer-grade-assessment/discussion/145253",
  "author_name": "Zac Dannelly",
  "post_date": "2020-04-22T12:13:56.772000",
  "votes": 14,
  "comment_count": 6,
  "views": 0,
  "content": "<p>(EDIT): Given the interest I changed the title to a more generic thread for anyone wanting to contribute. If you leave comments I can add them to this top Topic for easy access. </p>\n\n<p>(EDIT-2): <a href=\"/tpmeli\">@tpmeli</a> has also collected some <a href=\"https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682\">amazing resources on his post</a> that wonderfully augment what's here!</p>\n\n<p>I wanted to contribute a short Literature Review on previous methods and approaches in order to help jump start the group. If this is useful I am happy to expand on either depth or breadth of the search just let me know. </p>\n\n<ol>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611751/\">Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies</a>\na.  Good into to the problem set and descriptions of pre-processing\nb. Sets baselines for other work as well as benchmarks of performance </p></li>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876324/\">Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis</a>\na. Longer and more generic for CNN's use across various cancers\nb. <a href=\"/geertlitjens\">@geertlitjens</a> is a contributing author and also working this Kaggle!</p></li>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484626/\">Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images</a>\na. Direct comparison on methodologies.\nb.  Results:On 333 tissue microarray cores from 231 participants with prostate cancer (mean [SD] age, 63.2 [6.3] years), 20-fold leave-patches-out CV resulted in mean (SD) accuracy of 97.8% (1.2%), sensitivity of 98.5% (1.0%), and specificity of 97.5% (1.2%) for classifying benign patches vs cancerous patches. </p></li>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089889/\">Automated Gleason grading of prostate cancer tissue microarrays via deep learning</a>\na. Nice Github Repo -&gt; <a href=\"https://github.com/eiriniar/gleason_CNN\">gleson_CNN</a></p></li>\n<li><p><a href=\"/wouterbulten\">@wouterbulten</a> - From the contributors as paper with more information on the background of the data and problems we encountered: \na. <a href=\"https://arxiv.org/abs/1907.01368\">Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology</a>\n-<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2819%2930738-7/fulltext\">Full Text</a>\nb. <a href=\"https://arxiv.org/abs/1907.07980\">Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology.</a>\n-<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2819%2930739-9/fulltext\">Full Text</a></p></li>\n</ol>",
  "messages": [
    {
      "id": 816547,
      "postDate": "2020-04-22T12:13:56.773Z",
      "content": "<p>(EDIT): Given the interest I changed the title to a more generic thread for anyone wanting to contribute. If you leave comments I can add them to this top Topic for easy access. </p>\n\n<p>(EDIT-2): <a href=\"/tpmeli\">@tpmeli</a> has also collected some <a href=\"https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682\">amazing resources on his post</a> that wonderfully augment what's here!</p>\n\n<p>I wanted to contribute a short Literature Review on previous methods and approaches in order to help jump start the group. If this is useful I am happy to expand on either depth or breadth of the search just let me know. </p>\n\n<ol>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611751/\">Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies</a>\na.  Good into to the problem set and descriptions of pre-processing\nb. Sets baselines for other work as well as benchmarks of performance </p></li>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876324/\">Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis</a>\na. Longer and more generic for CNN's use across various cancers\nb. <a href=\"/geertlitjens\">@geertlitjens</a> is a contributing author and also working this Kaggle!</p></li>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484626/\">Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images</a>\na. Direct comparison on methodologies.\nb.  Results:On 333 tissue microarray cores from 231 participants with prostate cancer (mean [SD] age, 63.2 [6.3] years), 20-fold leave-patches-out CV resulted in mean (SD) accuracy of 97.8% (1.2%), sensitivity of 98.5% (1.0%), and specificity of 97.5% (1.2%) for classifying benign patches vs cancerous patches. </p></li>\n<li><p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089889/\">Automated Gleason grading of prostate cancer tissue microarrays via deep learning</a>\na. Nice Github Repo -&gt; <a href=\"https://github.com/eiriniar/gleason_CNN\">gleson_CNN</a></p></li>\n<li><p><a href=\"/wouterbulten\">@wouterbulten</a> - From the contributors as paper with more information on the background of the data and problems we encountered: \na. <a href=\"https://arxiv.org/abs/1907.01368\">Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology</a>\n-<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2819%2930738-7/fulltext\">Full Text</a>\nb. <a href=\"https://arxiv.org/abs/1907.07980\">Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology.</a>\n-<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2819%2930739-9/fulltext\">Full Text</a></p></li>\n</ol>",
      "rawMarkdown": "(EDIT): Given the interest I changed the title to a more generic thread for anyone wanting to contribute. If you leave comments I can add them to this top Topic for easy access. \n\n(EDIT-2): @tpmeli has also collected some [amazing resources on his post](https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682) that wonderfully augment what's here!\n\nI wanted to contribute a short Literature Review on previous methods and approaches in order to help jump start the group. If this is useful I am happy to expand on either depth or breadth of the search just let me know. \n\n1. [Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611751/)\na.  Good into to the problem set and descriptions of pre-processing\nb. Sets baselines for other work as well as benchmarks of performance \n\n2. [Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876324/)\na. Longer and more generic for CNN's use across various cancers\nb. @geertlitjens is a contributing author and also working this Kaggle!\n\n3. [Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484626/)\na. Direct comparison on methodologies.\nb.  Results:On 333 tissue microarray cores from 231 participants with prostate cancer (mean [SD] age, 63.2 [6.3] years), 20-fold leave-patches-out CV resulted in mean (SD) accuracy of 97.8% (1.2%), sensitivity of 98.5% (1.0%), and specificity of 97.5% (1.2%) for classifying benign patches vs cancerous patches. \n\n4. [Automated Gleason grading of prostate cancer tissue microarrays via deep learning](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089889/)\na. Nice Github Repo -&gt; [gleson_CNN](https://github.com/eiriniar/gleason_CNN)\n\n5. @wouterbulten - From the contributors as paper with more information on the background of the data and problems we encountered: \na. [Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology](https://arxiv.org/abs/1907.01368)\n   -[Full Text](https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext)\nb. [Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology.](https://arxiv.org/abs/1907.07980)\n  -[Full Text](https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext)",
      "votes": 13
    },
    {
      "id": 819485,
      "postDate": "2020-04-24T16:13:53.357Z",
      "content": "<p>Completely awesome.  I linked to you in a <a href=\"https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682\">similar post</a> I did.  Thanks for sharing!</p>",
      "rawMarkdown": "Completely awesome.  I linked to you in a [similar post](https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682) I did.  Thanks for sharing!",
      "votes": 1,
      "replies": [
        {
          "id": 819614,
          "postDate": "2020-04-24T17:57:01.833Z",
          "content": "<p>Awesome, to I'll do the same to make sure no one misses out if they only come across one 👍 </p>",
          "rawMarkdown": "Awesome, to I'll do the same to make sure no one misses out if they only come across one 👍 ",
          "votes": 1
        }
      ]
    },
    {
      "id": 816636,
      "postDate": "2020-04-22T13:34:46.930Z",
      "content": "<p>Nice overview! If you want to do a deep-dive and are interested in the work we have been doing before this competition, I can recommend these two articles:</p>\n\n<ul>\n<li>Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology. (freely accessible preprint here: <a href=\"https://arxiv.org/abs/1907.01368\">https://arxiv.org/abs/1907.01368</a>)\n<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext\">https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext</a></li>\n<li>Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology. (freely accesible preprint here: <a href=\"https://arxiv.org/abs/1907.07980\">https://arxiv.org/abs/1907.07980</a>)\n<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext\">https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext</a></li>\n</ul>\n\n<p>These papers also contain more information on the background of the data and problems we encountered.</p>",
      "rawMarkdown": "Nice overview! If you want to do a deep-dive and are interested in the work we have been doing before this competition, I can recommend these two articles:\n\n- Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology. (freely accessible preprint here: https://arxiv.org/abs/1907.01368)\nhttps://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext\n- Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology. (freely accesible preprint here: https://arxiv.org/abs/1907.07980)\nhttps://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext\n\nThese papers also contain more information on the background of the data and problems we encountered.",
      "votes": 2,
      "replies": [
        {
          "id": 816673,
          "postDate": "2020-04-22T14:01:04.720Z",
          "content": "<p>Awesome thanks! I edited the post some as I think it can just serve as a ongoing thread. </p>",
          "rawMarkdown": "Awesome thanks! I edited the post some as I think it can just serve as a ongoing thread. ",
          "votes": 2
        },
        {
          "id": 816680,
          "postDate": "2020-04-22T14:06:43.620Z",
          "content": "<p>Added these papers to the top thread!</p>",
          "rawMarkdown": "Added these papers to the top thread!",
          "votes": 1
        }
      ]
    },
    {
      "id": 816573,
      "postDate": "2020-04-22T12:40:17.857Z",
      "content": "<p>Thanks for sharing.</p>",
      "rawMarkdown": "Thanks for sharing.",
      "votes": 1
    }
  ],
  "comments": [
    {
      "id": 819485,
      "author_name": "Tom M",
      "author_url": "",
      "post_date": "2020-04-24T16:13:53.357000",
      "content": "<p>Completely awesome.  I linked to you in a <a href=\"https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682\">similar post</a> I did.  Thanks for sharing!</p>",
      "votes": 1,
      "replies": [
        {
          "id": 819614,
          "author_name": "Zac Dannelly",
          "author_url": "",
          "post_date": "2020-04-24T17:57:01.833000",
          "content": "<p>Awesome, to I'll do the same to make sure no one misses out if they only come across one 👍 </p>",
          "votes": 1,
          "replies": []
        }
      ]
    },
    {
      "id": 816636,
      "author_name": "Wouter Bulten",
      "author_url": "",
      "post_date": "2020-04-22T13:34:46.930000",
      "content": "<p>Nice overview! If you want to do a deep-dive and are interested in the work we have been doing before this competition, I can recommend these two articles:</p>\n\n<ul>\n<li>Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology. (freely accessible preprint here: <a href=\"https://arxiv.org/abs/1907.01368\">https://arxiv.org/abs/1907.01368</a>)\n<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext\">https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext</a></li>\n<li>Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology. (freely accesible preprint here: <a href=\"https://arxiv.org/abs/1907.07980\">https://arxiv.org/abs/1907.07980</a>)\n<a href=\"https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext\">https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext</a></li>\n</ul>\n\n<p>These papers also contain more information on the background of the data and problems we encountered.</p>",
      "votes": 2,
      "replies": [
        {
          "id": 816673,
          "author_name": "Zac Dannelly",
          "author_url": "",
          "post_date": "2020-04-22T14:01:04.720000",
          "content": "<p>Awesome thanks! I edited the post some as I think it can just serve as a ongoing thread. </p>",
          "votes": 2,
          "replies": []
        },
        {
          "id": 816680,
          "author_name": "Zac Dannelly",
          "author_url": "",
          "post_date": "2020-04-22T14:06:43.620000",
          "content": "<p>Added these papers to the top thread!</p>",
          "votes": 1,
          "replies": []
        }
      ]
    },
    {
      "id": 816573,
      "author_name": "Dracarys",
      "author_url": "",
      "post_date": "2020-04-22T12:40:17.857000",
      "content": "<p>Thanks for sharing.</p>",
      "votes": 1,
      "replies": []
    }
  ],
  "raw_markdown_by_id": {
    "816547": "(EDIT): Given the interest I changed the title to a more generic thread for anyone wanting to contribute. If you leave comments I can add them to this top Topic for easy access. \n\n(EDIT-2): @tpmeli has also collected some [amazing resources on his post](https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682) that wonderfully augment what's here!\n\nI wanted to contribute a short Literature Review on previous methods and approaches in order to help jump start the group. If this is useful I am happy to expand on either depth or breadth of the search just let me know. \n\n1. [Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611751/)\na.  Good into to the problem set and descriptions of pre-processing\nb. Sets baselines for other work as well as benchmarks of performance \n\n2. [Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876324/)\na. Longer and more generic for CNN's use across various cancers\nb. @geertlitjens is a contributing author and also working this Kaggle!\n\n3. [Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484626/)\na. Direct comparison on methodologies.\nb.  Results:On 333 tissue microarray cores from 231 participants with prostate cancer (mean [SD] age, 63.2 [6.3] years), 20-fold leave-patches-out CV resulted in mean (SD) accuracy of 97.8% (1.2%), sensitivity of 98.5% (1.0%), and specificity of 97.5% (1.2%) for classifying benign patches vs cancerous patches. \n\n4. [Automated Gleason grading of prostate cancer tissue microarrays via deep learning](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089889/)\na. Nice Github Repo -&gt; [gleson_CNN](https://github.com/eiriniar/gleason_CNN)\n\n5. @wouterbulten - From the contributors as paper with more information on the background of the data and problems we encountered: \na. [Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology](https://arxiv.org/abs/1907.01368)\n   -[Full Text](https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext)\nb. [Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology.](https://arxiv.org/abs/1907.07980)\n  -[Full Text](https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext)",
    "819485": "Completely awesome.  I linked to you in a [similar post](https://www.kaggle.com/c/prostate-cancer-grade-assessment/discussion/145682) I did.  Thanks for sharing!",
    "816636": "Nice overview! If you want to do a deep-dive and are interested in the work we have been doing before this competition, I can recommend these two articles:\n\n- Ström &amp; Kartasalo et al., 2020. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. The Lancet Oncology. (freely accessible preprint here: https://arxiv.org/abs/1907.01368)\nhttps://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30738-7/fulltext\n- Bulten et al., 2020. Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study. The Lancet Oncology. (freely accesible preprint here: https://arxiv.org/abs/1907.07980)\nhttps://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30739-9/fulltext\n\nThese papers also contain more information on the background of the data and problems we encountered.",
    "816573": "Thanks for sharing."
  }
}