{
  "competition": "cafa-5-protein-function-prediction",
  "topic_id": "412726",
  "comments": [],
  "messages": [],
  "raw_show": {
    "topic": {
      "id": 412726,
      "title": "How much to learn about Protein Functions?",
      "authorName": "Bibhash Ranjan Choudhury",
      "commentCount": 4,
      "votes": 3,
      "postDate": "2023-05-25T02:12:27.410000"
    },
    "comments": [
      {
        "id": 2273387,
        "authorName": "ZMC",
        "votes": 3,
        "postDate": "2023-05-25T06:20:01.330000",
        "content": "<p>as a largely wet-lab based biologist my personal perspective has been that domain knowledge of proteins has been of only very limited utility.. the problem here feels heavily data science oriented :p</p>"
      },
      {
        "id": 2291498,
        "authorName": "faarhaam",
        "votes": 1,
        "postDate": "2023-06-07T15:35:57.277000",
        "content": "<p>Yes, you must have an understanding of genetic concepts such as DNA, RNA, protein, then gene expression data and statistical analysis of that data.</p>"
      },
      {
        "id": 2291313,
        "authorName": "Helena Dolan",
        "votes": 1,
        "postDate": "2023-06-07T13:18:50.103000",
        "content": "<p>The Rosalind project is an excellent introduction to Bioinformatics - it may help you translate a little of the necessary domain knowledge. </p>"
      },
      {
        "id": 2273093,
        "authorName": "Lorenzo Polidori",
        "votes": 2,
        "postDate": "2023-05-25T02:27:16.187000",
        "content": "<p>Hello 👋 <br>\nDomain knowledge is definitely helpful. However, reading the papers and the suggestions that other Kagglers provided might help you getting started. Overall, in depth knowledge is not a strict requirement but diving deep in the problem will help you for sure! My suggestions are:</p>\n<ul>\n<li>read papers on this matter and gene ontology predictions </li>\n<li>read kernels from other Kagglers and their discussions</li>\n<li>start exploring the data and understanding the underlying problems</li>\n</ul>\n<p>Hope this is helpful!</p>"
      }
    ]
  },
  "topic": null,
  "index": {
    "id": "412726",
    "title": "How much to learn about Protein Functions?",
    "authorName": "",
    "commentCount": "4",
    "votes": "3",
    "postDate": "2023-05-25 02:12:27.410000"
  }
}